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广州为华生物双端氨基聚乙二醇NH2-PEG-NH2可应用于多肽,蛋白等药物分子修饰

发表时间:2022-10-21

为华生物双端氨基聚乙二醇NH2-PEG-NH2可应用于多肽,蛋白等药物分子修饰

为华生物NH2-PEG-NH2氨基聚乙二醇氨基储存条件2-8°C,溶解度:溶于大部分有机溶剂,不溶于水

形态:白色固体粉末状,或粘稠液体取决于PEG分子量。

NH2-PEG-NH2是一类同双官能团修饰剂,可用于靶向药物研究并广泛应用于蛋白载体及配基的交联等。产品的氨基端,对于酰化试剂活性比羟基高,它很容易进行还原氨基化反应。应用氨基的反应活性,容易进行还原氨基化反应,生成稳定的化学键如酰胺键,氨基甲酸酯键,脲键和仲胺键等把另一些分子和其连接。广泛应用于多肽,蛋白等药物分子的修饰。

为华生物NH2-PEG-NH2氨基聚乙二醇氨基可用于:制备带有生物活性化合物的配体;多肽合成时的载体;制备高分子接枝物等等

注意事项:NH2-PEG-NH2氨基聚乙二醇氨基易吸潮,取用前需放置室温后再打开包装取用防止吸潮,吸潮后活性会降低直至完全失去活性,请务必保持干燥同时尽量避免频繁的溶解和冻干。

 

Nh2-peg-nh2 amino polyethylene glycol amino storage conditions 2-8 ° C, solubility: soluble in most organic solvents, insoluble in water

 

Form: white solid powder, or viscous liquid, depending on the molecular weight of PEG.

 

Nh2-peg-nh2 is a kind of bifunctional modifier, which can be used in targeted drug research and widely used in protein carrier and ligand crosslinking. The amino end of the product is more active than the hydroxyl group for the acylation reagent, and it is easy to carry out the reductive amino reaction. Using the reactive activity of amino groups, it is easy to carry out reductive amino reactions, generate stable chemical bonds such as amide bonds, carbamate bonds, urea bonds and secondary amine bonds, and connect other molecules with them. It is widely used in the modification of drug molecules such as polypeptides and proteins.

 

The nh2-peg-nh2 amino polyethylene glycol amino group of sinobio can be used to: prepare ligands with bioactive compounds; Carrier for polypeptide synthesis; Preparation of polymer grafts and the like.

 

Precautions: nh2-peg-nh2 amino polyethylene glycol amino group is easy to absorb moisture. Before taking it, it needs to be placed at room temperature before opening the package to prevent moisture absorption. After moisture absorption, the activity will decrease until it completely loses its activity. Please keep it dry and avoid frequent dissolution and lyophilization.